GNM-X vs Protandim: two Nrf2 activators, label to label

GNM-X and Protandim Nrf2 Synergizer both switch on Nrf2, with different formulas. GNM-X uses three extracts (rosemary, ginger and Sophora japonica) and no caffeine; Protandim uses five and carries 1.8 mg of caffeine. Both are one capsule a day. On price, GNM-X's 6-Pack is $41.65 a bottle with no subscription.

What's in each formula

GNM-X (Activz)Protandim Nrf2 Synergizer (LifeVantage)
Nrf2 extractsRosemary leaf, ginger root, Sophora japonica bud (luteolin)Bacopa, milk thistle, ashwagandha, green tea, turmeric
Amount on the label91 mg blend + 7 mg niacin (44% DV)Blend, amount per extract not published
CaffeineNone1.8 mg per caplet
Dose1 capsule a day1 caplet a day, with food
Per bottle30 capsules (30 days)30 caplets (30 days)

The practical difference is focus. GNM-X puts three extracts on the same switch: carnosic acid from rosemary binds KEAP1, the protein that holds Nrf2 back, and ginger's 6-shogaol and Sophora's luteolin release Nrf2 too. Together, in a 10:5:1 ratio, they activated Nrf2 in human liver cells (Hybertson et al., 2022, PMID 35252766). And with no caffeine, it fits in the evening as well as the morning.

Price per bottle, with and without a subscription

How you buyGNM-XProtandim
One bottle, one-time$63.75$66.99
Lowest price per bottle$41.65 (6-Pack, one-time)$60.29 (monthly subscription)
Subscription required for the low priceNoYes, Subscribe & Save
On AmazonVaries by seller; official price here$76.99 a bottle

Protandim prices are from LifeVantage's US store as of September 16, 2026. GNM-X's are the official US price, with free USPS shipping in 2–5 business days and nothing that renews on its own: you order again when you want to.

Looking for a Protandim alternative?

If you already take Protandim and want to switch, GNM-X is the same routine (one capsule a day) with a different, caffeine-free formula aimed at the same Nrf2 switch. Start with one bottle at $63.75 for a month, or take the 6-Pack and pay $41.65 a bottle without signing up for anything.

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GNM-X prices in the US

One capsule a day, 30 capsules a bottle: each bottle is a month. Free USPS shipping in 2–5 business days, and no subscription.